GeneticsbioRxivPreprint
An image-based CRISPR screen reveals splicing-mediated control of HP1α condensates
Matthew Man-Kin Wong, Shaopu Zhou, Chris Carpenter…·Serena Sanulli
The paper uses an image-based CRISPR screen to show splicing regulates HP1α condensates through RNA-chromatin interactions, affecting heterochromatin organization and stress response genes.
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