Elena M. Vazey

This study shows that chronic alcohol and stress exposure in midlife leads to persistent cognitive impairments and locus coeruleus pathology in mice.

This study shows that low affinity noradrenergic signaling shifts behavior from active avoidance to passive coping during reinforcement tasks, with sex differences observed in reward seeking.

This study analyzes LC neuron firing patterns across species and biological factors, revealing diverse activity patterns and subregions enriched for specific factors and disease models.

This paper develops a method for binge-like ethanol consumption in head-fixed mice and uses two-photon calcium imaging to study its effects on prefrontal cortex neuron activity.

This study shows that beta-adrenergic signaling in the premotor cortex is critical for suppressing irrelevant information during decision making, with sex-dependent effects observed in rats.

The paper shows that less flexible mice consume more ethanol, linking behavioral inflexibility to higher alcohol intake.

This study shows that voluntary alcohol consumption disrupts the coupling between prefrontal cortical activity and arousal in mice.

This study investigates the role of norepinephrine projections from the locus coeruleus to the central amygdala in defensive responses to learned threats, showing bidirectional modulation of freezing behavior.