Author

Alan G. Mackay

Institute of Cancer ResearchORCID 0000-0003-3323-4017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chris JonesiD· 3 shared Alexandra Saint‐CharlesiD· 1 shared Andreas SchlickeriD· 1 shared Angel Montero CarcabosoiD· 1 shared Angela Di GiannataleiD· 1 shared Angelika EggertiD· 1 shared Aniello FedericoiD· 1 shared Anna Burford· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

Chris JonesORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 23, 2026

Combination of ALK2 and cholesterol targeting agents exploits linked genetic and metabolic dependencies in diffuse midline glioma

Rebecca Rogers, Alan G. Mackay, Yura Grabovska…·Chris Jones

This study identifies a combinatorial strategy using ALK2 inhibitors and statins to target metabolic dependencies in diffuse midline glioma.

DOI 10.64898/2026.09.23.753440

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintFeb 9, 2026

The ITCC-P4 PDX platform of pediatric cancers for preclinical testing

Aniello Federico, Apurva Gopisetty, Didier Surdez…·Gudrun Schleiermacher

The paper introduces a PDX platform for pediatric cancers, providing in vivo drug testing models and molecular data to aid in therapy development.

2 citations

humanexperimental assay

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GenomicsbioRxivPreprintFeb 24, 2023

Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars

Kasey Skinner, Tomoyuki Koga, Shunichiro Miki…·Frank B. Furnari

This study develops human iPSC-derived tumor models to investigate the cooperative effects of H3.3K27M and PDGFRA mutations in DMG, identifying therapeutic vulnerabilities.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky