GenomicsbioRxivPreprint
Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars
Kasey Skinner, Tomoyuki Koga, Shunichiro Miki…·Frank B. Furnari
This study develops human iPSC-derived tumor models to investigate the cooperative effects of H3.3K27M and PDGFRA mutations in DMG, identifying therapeutic vulnerabilities.
3 citations