Author

Yun‐Kyo Kim

Hospital for Sick ChildrenORCID 0000-0003-3349-2841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Miguel Ramalho‐SantosiD· 2 shared Andrew J.K. WilliamsoniD· 1 shared Anthony David WhettoniD· 1 shared Aydan Bulut-KarslıoğluiD· 1 shared Bin GuiD· 1 shared Brandon ChoiD· 1 shared Elizabeth K. Woolaver· 1 shared Evan Thomas· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Miguel Ramalho‐SantosORCID

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3 papers

Recent·Most cited

Developmental BiologyScience AdvancesPeer-reviewedJul 19, 2024

Durotaxis bridges phase transition as a function of tissue stiffness in vivo

Min Zhu, Bin Gu, Evan Thomas…·Sevan Hopyan

The paper shows that fibronectin-dependent tissue stiffness controls durotaxis and cell rearrangements through a phase transition model in mouse limb bud mesoderm.

10 citations

mousestatistical model

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GenomicsbioRxivPreprintDec 13, 2021

Absolute Scaling of Single-Cell Transcriptomes Reveals Pervasive Hypertranscription in Adult Stem and Progenitor Cells

Yun‐Kyo Kim, Miguel Ramalho‐Santos

The paper introduces absolute scaling for single-cell RNA-seq to estimate total transcript abundances, revealing hypertranscription in adult stem and progenitor cells across multiple tissues.

1 citation

mousescRNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedAug 11, 2021

Chd1 regulates repair of promoter-proximal DNA breaks to sustain hypertranscription in embryonic stem cells

Aydan Bulut-Karslıoğlu, Hu Jin, Yun‐Kyo Kim…·Miguel Ramalho‐Santos

This study identifies Chd1's role in repairing DNA breaks in embryonic stem cells, showing its importance in maintaining hypertranscription during development.

24 citations

mouseDNA methylation

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