Isabel Risch

The paper identifies a broader pathogenic T cell receptor motif linked to HLA-B*27-associated autoimmune diseases and shows these T cells express a Type 17 program.

This study uses single-cell RNA sequencing to analyze Kaposi Sarcoma tumors and blood samples, identifying KSHV-infected cell types and their biomarkers, and showing changes with therapy.

This study shows that USP7 deletion in mice causes neurological phenotypes, including synaptic proteome changes and dendritic spine defects, independent of p53.

scMINER identifies hidden drivers and network rewiring in single-cell RNA-seq data using mutual information, outperforming existing methods in clustering and network inference.