Author

Jun-Ichi Sakamaki

Juntendo UniversityORCID 0000-0003-3361-6314Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Fumiyo IkedaiD· 1 shared Hiromi Nishimura· 1 shared Masaaki KomatsuiD· 1 shared Minori Miyasaka· 1 shared Stephanie KaypeeiD· 1 shared Takuto NAKAJIMA· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

Fumiyo IkedaORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintJan 20, 2026

Excess Met1-ubiquitination leads to solid aggregate formation

Stephanie Kaypee, Minori Miyasaka, Takuto NAKAJIMA…·Fumiyo Ikeda

This study shows that reduced HOIL-1 activity increases Met1-ubiquitin chains, leading to solid protein aggregates and impaired autophagy in neurodegenerative diseases.

1 citation

humanproteomics

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