Meagan N. Olson

This study develops a high-throughput platform using human cerebral organoids to screen for compounds that reverse HSV-1-induced neuroinflammation biomarkers associated with Alzheimer's disease.

The paper screens cerebrospinal fluid from MS and non-MS patients using a multiplex peptide library to identify microbial and autoantigenic epitopes enriched in MS.

The paper introduces a method to multiplex reprogram somatic cells into iPSCs and estimates donor contributions using pooled sequencing and SNPs, finding consistent reprogramming ability across donors.

The paper investigates the association between mitochondrial variant MT:10398A>G and heteroplasmy in brain tissue and lymphoblastoid cell lines, identifying its role in mitochondrial function and disease phenotypes.