Nathaniel Barton

This study develops a high-throughput platform using human cerebral organoids to screen for compounds that reverse HSV-1-induced neuroinflammation biomarkers associated with Alzheimer's disease.

The paper screens cerebrospinal fluid from MS and non-MS patients using a multiplex peptide library to identify microbial and autoantigenic epitopes enriched in MS.

The paper investigates the association between mitochondrial variant MT:10398A>G and heteroplasmy in brain tissue and lymphoblastoid cell lines, identifying its role in mitochondrial function and disease phenotypes.

SLALOM rapidly generates CRISPR-Cas9 sgRNA libraries from DNA in under 3 hours, enabling efficient and cost-effective library synthesis for various biological applications.