Author

Nina-Lydia Kazakou

MRC Centre for Regenerative MedicineORCID 0000-0003-3381-2390Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Anna WilliamsiD· 2 shared Luise A. SeekeriD· 2 shared Nadine Bestard-Cuche· 2 shared Neil Cowan HendersoniD· 2 shared Sarah JäkeliD· 2 shared Sunniva M. K. BøstrandiD· 2 shared Agnete KirkebyiD· 1 shared Alastair Morris KilpatrickiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersNeuroscience

Anna WilliamsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceScience AdvancesPeer-reviewedSep 2, 2026

Activation of transposable elements is linked to a region- and cell-type-specific interferon response in Parkinson's disease

Raquel Garza, Anita Adami, Arun Thiruvalluvan…·Johan Jakobsson

The paper investigates TE transcription in Parkinson's disease brains, finding region- and cell-type-specific TE activation linked to an interferon response in microglia and neurons.

DOI 10.1126/sciadv.aed2952

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedOct 20, 2024

Mapping the glial transcriptome in Huntington's disease using snRNAseq: Selective disruption of glial signatures across brain regions

Sunniva M. K. Bøstrand, Luise A. Seeker, Nadine Bestard-Cuche…·Anna Williams

This study uses snRNAseq to analyze glial cell heterogeneity in Huntington's disease across brain regions, identifying subtype-specific changes and potential mechanisms of glial dysfunction.

11 citations

humansnRNA-seq

𝕏 PostBluesky

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedMay 22, 2023

Marked regional glial heterogeneity in the human white matter of the central nervous system

Luise A. Seeker, Nadine Bestard-Cuche, Sarah Jäkel…·Anna Williams

The paper identifies regional glial heterogeneity in human white matter using single nucleus RNA sequencing, revealing tissue-specific glial populations and age/sex-related gene expression differences.

66 citationstop 2%

humanscRNA-seq

𝕏 PostBluesky