Sunniva M. K. Bøstrand

This study uses snRNAseq to analyze glial cell heterogeneity in Huntington's disease across brain regions, identifying subtype-specific changes and potential mechanisms of glial dysfunction.

The paper identifies regional glial heterogeneity in human white matter using single nucleus RNA sequencing, revealing tissue-specific glial populations and age/sex-related gene expression differences.

This study shows that INPP5E negatively regulates Sonic Hedgehog signaling in human cortical organoids, promoting dorsal telencephalic identity and preventing ventralization.

This study shows that TET1-mediated DNA hydroxy-methylation is essential for adult remyelination, with loss of function leading to impaired myelin repair in aged mice.