William Thomas Keenan

Deleting Piezo1 and Piezo2 together in mice weakens uterine contractions and prolongs labor; uterine and sensory-neuron deletions act additively, and knockout uteri show reduced Gja1 (connexin43).

This study shows satellite glia are essential for sympathetic neuron survival, activity, and autonomic function in mice, with implications for cardiovascular disease and hypertension.