PhysiologySciencePeer-reviewed
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PIEZO channels link mechanical forces to uterine contractions in parturition
Yunxiao Zhang, Sejal A Kini, Sassan A Mishkanian…·Ardem Patapoutian
Deleting Piezo1 and Piezo2 together in mice weakens uterine contractions and prolongs labor; uterine and sensory-neuron deletions act additively, and knockout uteri show reduced Gja1 (connexin43).