Author

John E. Froberg

Harvard UniversityORCID 0000-0003-3391-7619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell-cell communication· 2 Assay:proteomics· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Jeffrey D. MacklisiD· 3 shared Bogdan BudnikiD· 2 shared Omer DurakiD· 2 shared Andrea J. KriziD· 1 shared Dustin E. TillmaniD· 1 shared George C. WheeleriD· 1 shared Jeannie T. LeeiD· 1 shared Phuoc Tien TraniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersNeuroscience

Jeffrey D. MacklisORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 12, 2026

Sequestration of growth cone surface proteins by cytoplasmic Lrrtm2 induces de novo amygdala innervation by cerebral cortex associative neurons

Dustin E. Tillman, Omer Durak, Priya Veeraraghavan…·Jeffrey D. Macklis

The paper identifies how Lrrtm2 sequestration in growth cones disrupts axon guidance, leading to abnormal amygdala innervation in callosal projection neurons, linking Bcl11a deletion to ASD/ID mechanisms.

DOI 10.64898/2026.04.08.716720

mouseproteomics

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NeurosciencebioRxivPreprintDec 22, 2024

Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositions

Phuoc Tien Tran, Bogdan Budnik, John E. Froberg, Jeffrey D. Macklis

The paper identifies subtype-specific ribosomal complex protein compositions in cortical projection neurons during axonal connectivity formation.

1 citation

mouseproteomics

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Molecular BiologybioRxivPreprintApr 5, 2022

Development of ultra-low-input nanoRibo-seq enables quantification of translational control, revealing broad uORF translation by subtype-specific neurons

John E. Froberg, Omer Durak, Jeffrey D. Macklis

The paper develops nanoRibo-seq, an ultra-low-input method for Ribo-seq, revealing uORF translation in specific neurons.

DOI 10.1101/2022.04.05.487068

mouseRibo-seq

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GenomicsNature CommunicationsPeer-reviewedNov 21, 2018

Megadomains and superloops form dynamically but are dispensable for X chromosome inactivation and gene escape

John E. Froberg, Stefan F. Pinter, Andrea J. Kriz…·Jeannie T. Lee

The paper investigates the role of megadomains and superloops in X chromosome inactivation, finding they are not required for silencing or gene escape.

66 citations

mouseChIP-seq

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