Author

Hans W. J. de Looper

Erasmus MCORCID 0000-0003-3416-7581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Cansu KoyunlariD· 2 shared Emanuele GioacchinoiD· 2 shared Emma de PateriD· 2 shared Eric M. BindelsiD· 2 shared Ivo P. TouwiD· 2 shared Joke ZinkiD· 2 shared Mathijs Arnoud SandersiD· 2 shared Remco Michiel HoogenboezemiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Cansu KoyunlarORCID

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2 papers

Recent·Most cited

Cell BiologyBlood AdvancesPeer-reviewedMar 26, 2025

Hematological phenotypes in GATA2 deficiency syndrome arise from secondary injuries and maladaptation to proliferation

Juncal Fernández‐Orth, Cansu Koyunlar, Julia Miriam Weiss…·Emma de Pater

This study shows that GATA2 deficiency leads to hematological issues through bone marrow failure and maladaptation, with leukemia arising from genomic instability and proliferation defects.

9 citationstop 3%

mousebulk RNA-seq

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Developmental BiologyBlood AdvancesPeer-reviewedJan 17, 2023

Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition

Cansu Koyunlar, Emanuele Gioacchino, Disha Vadgama…·Emma de Pater

This study shows that Gata2 regulates Gfi1b to control endothelial-to-hematopoietic transition and HSPC maturation, with reduced Gata2 leading to impaired hematopoietic programming.

14 citations

mousezebrafish

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