Cansu Koyunlar

This study shows that GATA2 deficiency leads to hematological issues through bone marrow failure and maladaptation, with leukemia arising from genomic instability and proliferation defects.

This study shows that Gata2 regulates Gfi1b to control endothelial-to-hematopoietic transition and HSPC maturation, with reduced Gata2 leading to impaired hematopoietic programming.

This study shows that zebrafish desmin gene knockouts do not cause skeletal muscle degeneration but alter calcium flux in myofibers.

This study shows that deleting a conserved zebrafish Gata2 enhancer impairs haemogenic endothelium programming and adult haematopoiesis, leading to bone marrow failure and immune defects.