Author

Emanuele Gioacchino

Erasmus MCORCID 0000-0002-2787-6286Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Cansu KoyunlariD· 2 shared Emma de PateriD· 2 shared Eric M. BindelsiD· 2 shared Hans W. J. de LooperiD· 2 shared Ivo P. TouwiD· 2 shared Joke ZinkiD· 2 shared Mathijs Arnoud SandersiD· 2 shared Remco Michiel HoogenboezemiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Cansu KoyunlarORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Hematological phenotypes in GATA2 deficiency syndrome arise from secondary injuries and maladaptation to proliferation

Juncal Fernández‐Orth, Cansu Koyunlar, Julia Miriam Weiss, Emanuele Gioacchino, Hans W. J. de Looper, Geoffroy Andrieux, Mariëtte ter Borg, Joke Zink, Irene González-Menéndez, Remco Michiel Hoogenboezem, Baris Yigit, Kirsten J. Gussinklo, Roger Mulet‐Lazaro, Charlotte Wantzen, Sophie Pfeiffer, , Emma de Pater

This study shows that GATA2 deficiency leads to hematological issues through bone marrow failure and maladaptation, with leukemia arising from genomic instability and proliferation defects.

Blood Advances · Mar 26, 2025Peer-reviewedCell Biology

Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition

Cansu Koyunlar, Emanuele Gioacchino, Disha Vadgama, Hans W. J. de Looper, Joke Zink, Mariëtte N. D. ter Borg, Remco Michiel Hoogenboezem, Marije Havermans, Mathijs Arnoud Sanders, Eric M. Bindels, Elaine Anne Dzierzak, Ivo P. Touw, Emma de Pater

This study shows that Gata2 regulates Gfi1b to control endothelial-to-hematopoietic transition and HSPC maturation, with reduced Gata2 leading to impaired hematopoietic programming.

Blood Advances · Jan 17, 2023Peer-reviewedDevelopmental Biology