NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Cryptic intronic transcriptional initiation generates efficient endogenous mRNA templates for C9orf72-associated RAN translation
Shannon L. Miller, Katelyn M. Green, Bradley Crone…·Peter K. Todd
The paper identifies cryptic intronic C9orf72 transcripts as endogenous templates for RAN translation, leading to DPR production in ALS/FTD.
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