Author

Patrick C. Hoffmann

Max Planck Institute of BiophysicsORCID 0000-0003-3421-6363Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Gerhard HummeriD· 3 shared Jan Philipp KreysingiD· 3 shared Martin BeckiD· 3 shared Agnieszka Obarska-KosińskaiD· 2 shared Beata TuroňováiD· 2 shared Katharina GeißleriD· 2 shared Sergio Cruz-LeóniD· 2 shared Alexander SchmidtiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCell Biology

Gerhard HummerORCID

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3 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedApr 21, 2026

The vault associates with membranes in situ

Katharina Geißler, Jan Philipp Kreysing, Yuning Wang…·Martin Beck

This study uses cryo-electron tomography to show vault particles associate with ER and nuclear envelope membranes and enclose ribosomes in Dictyostelium discoideum.

1 citation

Drosophilacryo-EM

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Cell BiologyMolecular CellPeer-reviewedDec 26, 2024

Nuclear pores as conduits for fluid flow during osmotic stress

Patrick C. Hoffmann, Hyuntae Kim, Agnieszka Obarska-Kosińska…·Martin Beck

This study shows that Dictyostelium discoideum uses nuclear pores as conduits for fluid flow during osmotic stress, distinct from passive diffusion and active transport.

46 citationstop 3%

Drosophilastatistical model

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Molecular BiologyNature CommunicationsPeer-reviewedMay 11, 2024

High-confidence 3D template matching for cryo-electron tomography

Sergio Cruz-León, Tomáš Majtner, Patrick C. Hoffmann…·Gerhard Hummer

This paper introduces a high-confidence 3D template matching method for CryoET, enabling accurate localization of cellular structures with improved statistical confidence.

83 citationstop 1%

imagingstatistical model

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