Beata Turoňová

The paper reports an extended structure of the human nuclear pore complex, revealing TREX-2 components as integral parts of the nuclear ring.

This study uses in situ structural biology to reveal the molecular organization of chromatin at the nuclear periphery in human cells.

cryoTIGER uses deep learning to generate intermediate tilt images in cryo-electron tomography, improving 3D reconstruction and structural recovery.

This study evaluates tilt increments in cryo-ET to find the optimal balance between image quality and radiation damage, recommending 3 degrees as the best increment.

This paper introduces TANGO, a framework for analyzing spatial arrangements of particles in cryo-ET using point cloud descriptors, enabling rotationally invariant feature extraction and exploratory analysis of cellular structures.

This study develops a deep learning method to automatically remove corrupted tilts in cryo-ET, showing high efficiency and reliability with trained models for direct application.

This study shows that nuclear pore complexes dilate during cell differentiation and that Nup133 deficiency prevents this dilation, leading to nuclear envelope instability.

This study investigates how HIV-1 capsids pass through nuclear pores, finding that capsids retain their structure and cause NPC scaffold rings to crack.

This study shows that Dictyostelium discoideum uses nuclear pores as conduits for fluid flow during osmotic stress, distinct from passive diffusion and active transport.

This paper introduces a high-confidence 3D template matching method for CryoET, enabling accurate localization of cellular structures with improved statistical confidence.

The paper identifies the palisade layer of the vaccinia virus core as composed of flexible A10 trimers using cryoET, STA, and AlphaFold2.

The paper uses AI to create a dynamic model of the human nuclear pore complex, showing how the protein scaffold interacts with the nuclear envelope.

This study uses cryo electron tomography and simulations to analyze the structure of SARS-CoV-2 spike protein in situ, revealing three hinges in the stalk domain that enable orientational flexibility.

This study benchmarks tomographic acquisition schemes for cryo electron tomography to optimize resolution for subtomogram averaging using HIV-1 lattice.