Author

Yuezhou Chen

Peking UniversityORCID 0000-0003-3453-1988Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Jiahe ZangiD· 1 shared Jiaxuan XuiD· 1 shared Lei CheniD· 1 shared Miao WeiiD· 1 shared Wenjun GuoiD· 1 shared Yunfeng LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Jiahe ZangORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedFeb 10, 2025

✦ In-depth digest

Mechanisms of urate transport and uricosuric drugs inhibition in human URAT1

Wenjun Guo, Miao Wei, Yunfeng Li…·Lei Chen

Cryo-EM structures of human URAT1 with urate, benzbromarone, or verinurad (3.0 to 3.3 Å) reveal a rocker-switch transport cycle and inhibitors that lock the inward-facing state.

35 citationstop 1%

humanprotein structure

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