Carla Bautista

This study uses population genomics and machine learning to identify genetic markers predictive of antifungal resistance in Candida albicans, highlighting the need for expanded resistance catalogues.

The paper shows that hybrid yeast adaptation is slowed by Haldane's sieve due to slower loss of heterozygosity and incomplete dominance of adaptive mutations.

This study shows that adaptation to complex environments involves trade-offs and pleiotropic effects, with mutations affecting multiple biological processes and recurrent gene targets.

Toeholder is a software tool for automated design and in silico validation of toehold riboswitches, incorporating experimental data and molecular dynamics simulations.