Author

Jan Soroczynski

Rockefeller UniversityORCID 0000-0003-3471-4637Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Assay:Hi-C· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

Hideaki KonishiiD· 2 shared Joanna Lan-Hing YeungiD· 2 shared Viviana I. RiscaiD· 2 shared Arnold OuiD· 1 shared Avaneesh V. NarlaiD· 1 shared Beverly NaiglesiD· 1 shared Conor WhelaniD· 1 shared Deena A. OreniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Hideaki KonishiORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 10, 2026

CAD-C: An engineered nuclease enables repair-free in situ proximity ligation and nucleosome-resolution chromosome walks in human cells

Jan Soroczynski, Lauren Anderson Westcott, Wu Zuo…·Viviana I. Risca

This paper introduces CAD-C, a new chromatin conformation capture method that improves resolution and efficiency over existing techniques like Micro-C and Hi-C.

3 citations

humanHi-C

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GenomicsbioRxivPreprintJul 11, 2024

OpenTn5: Open-Source Resource for Robust and Scalable Tn5 Transposase Purification and Characterization

Jan Soroczynski, Lauren J. Anderson, Joanna Lan-Hing Yeung…·Viviana I. Risca

The paper introduces an open-source protocol for producing and characterizing hyperactive Tn5 transposase for use in various sequencing applications.

15 citations

E. coliATAC-seq

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Systems BiologyJournal of Biological ChemistryPeer-reviewedSep 9, 2023

Quantifying dynamic pro-inflammatory gene expression and heterogeneity in single macrophage cells

Beverly Naigles, Avaneesh V. Narla, Jan Soroczynski…·Nan Hao

This study investigates how dynamic interferon-gamma stimulation affects pro-inflammatory gene expression in macrophages, revealing gene-specific response patterns and stochasticity in CXCL10 expression.

12 citations

mousespatial transcriptomics

𝕏 PostBluesky