Joanna Lan-Hing Yeung

CAD-C: An engineered nuclease enables repair-free in situ proximity ligation and nucleosome-resolution chromosome walks in human cells

This paper introduces CAD-C, a new chromatin conformation capture method that improves resolution and efficiency over existing techniques like Micro-C and Hi-C.

CDK4/6 inhibition induces a DNA damage-independent senescence-associated secretory phenotype driven by delayed activation of NF-κB

This study compares the SASP and transcriptional profiles induced by CDK4/6 inhibitors and DNA damage, revealing delayed NF-κB activation in CDK4/6i.

OpenTn5: Open-Source Resource for Robust and Scalable Tn5 Transposase Purification and Characterization

The paper introduces an open-source protocol for producing and characterizing hyperactive Tn5 transposase for use in various sequencing applications.