PARP1/2-linked ADP-ribosylation impairs trophoblast mitochondrial respiration in a TNF-α model of inflammation-mediated preeclampsia.
Abolfazl Nik-Akhtar, Sophia Vanegas Pineda, Jacob Ouellet…·Shannon A. Bainbridge
This study shows PARP1/2-linked ADP-ribosylation impairs trophoblast mitochondrial respiration in inflammation-mediated preeclampsia, with olaparib improving respiration.