Author

Keir J. Menzies

University of OttawaORCID 0000-0002-1873-8500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Abolfazl Nik-AkhtariD· 2 shared Fahmida Jahan· 2 shared Shannon A. BainbridgeiD· 2 shared Yusmaris CariacoiD· 2 shared Alex Green· 1 shared Andrew I. MikhailiD· 1 shared Changhyun LimiD· 1 shared Derek William StouthiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Abolfazl Nik-AkhtarORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 21, 2026

PARP1/2-linked ADP-ribosylation impairs trophoblast mitochondrial respiration in a TNF-α model of inflammation-mediated preeclampsia.

Abolfazl Nik-Akhtar, Sophia Vanegas Pineda, Jacob Ouellet…·Shannon A. Bainbridge

This study shows PARP1/2-linked ADP-ribosylation impairs trophoblast mitochondrial respiration in inflammation-mediated preeclampsia, with olaparib improving respiration.

DOI 10.64898/2026.10.20.758860

humanrat

𝕏 PostBluesky

PhysiologybioRxivPreprintSep 15, 2026

Arginine methyltransferase signalling is hyperactive in conditions of neuromuscular junction instability and muscle atrophy

Andrew I. Mikhail, Sean Y. Ng, Magda A. Lesinski…·Vladimir Ljubicic

This study shows that CARM1 activity increases in neuromuscular junction instability and muscle atrophy in mice and humans, correlating with NMJ dysfunction and muscle health decline.

DOI 10.64898/2026.09.09.750242

mousehuman

𝕏 PostBluesky

Molecular BiologybioRxivPreprintSep 9, 2023

NAD+ depletion and altered mitochondrial function are key to the establishment of placental dysfunction in an inflammatory-driven subclass of preeclampsia

Fahmida Jahan, Goutham Vasam, Yusmaris Cariaco…·Shannon A. Bainbridge

Boosting NAD+ levels prevent inflammatory-driven preeclampsia by improving placental mitochondrial function.

DOI 10.1101/2023.09.09.556974

humanmouse

𝕏 PostBluesky