The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signalling
Lilian C. Russo, Rebeka Tomasin, Isaac de Araújo Matos, Antonio Carlos Manucci, Sven T. Sowa, Katie L. Dale, Keith W. Caldecott, L. Lehtiö, Deborah Schechtman, Flávia Carla Meotti, Alexandre Bruni‐Cardoso, Nícolas C. Hoch
This paper shows that the SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling in human cells.
Journal of Biological Chemistry · Aug 4, 2021Peer-reviewedMolecular Biology