Deborah Schechtman

The paper constructs and compares PPI networks of drug targets in nociceptor subtypes across mouse and human DRGs, revealing species-specific conservation and broader cellular roles of key drug targets.

This study shows that PLCγ modulates TRP channel expression and activity during neuropathic pain development, with TAT-pQYP reversing mechanical hypersensitivity by targeting PLCγ.

This study investigates the role of aPKC paralogs in mouse brain development and survival, finding that their function is critical during a specific window of neural progenitor differentiation but less essential afterward.

This paper shows that the SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling in human cells.