Joyce To

This study analyzes 1,740 Vibrio cholerae genomes to show that anti-phage defence systems and multidrug resistance co-disseminate via mobile genetic elements, with non-O1 strains harboring more diverse defences and O1 strains showing stronger associations between defence systems and AMR.

This study evolves three bacterial species in single- and mixed-species biofilms, showing mixed-species interactions constrain diversification while promoting specific adaptive mutations.

The paper profiles Burkholderia pseudomallei variants from clinical isolates to understand colony morphotype variation (CMV) using proteomics and genomics, finding that CMV is driven by regulatory mechanisms rather than genomic mutations.

The paper identifies two genetically distinct Burkholderia pseudomallei strains co-isolated from a single patient and presents their multi-omics characterization.

This paper develops a machine learning framework to predict symptomatic and asymptomatic bacteriuria in spinal cord injury patients using microbiome data, achieving high accuracy in classification.

This study develops a mixed-species urinary catheter biofilm model from spinal cord injury patients to better understand and treat catheter-associated infections.

Hackflex is a low-cost method for Illumina library prep that produces high-quality, uniform libraries at 14 times lower cost than standard Nextera Flex.