Kay A. Ramsay

Disruption of cAMP Signalling and RNA Regulation Confers Cefiderocol Resistance in Acinetobacter baumannii

This study identifies two mechanisms of cefiderocol resistance in Acinetobacter baumannii: cAMP signalling disruption and Hfq RNA-binding domain truncation, both linked to iron homeostasis and reduced drug activity.

Cross-species convergence of surface polysaccharides shapes the virulence of an atypical carbapenem resistant uropathogenic Escherichia coli clone

The paper identifies a new carbapenem-resistant E. coli clone, ST361, associated with UTI and shows its virulence is linked to surface polysaccharides and mobile genetic elements.

Profiling of Burkholderia pseudomallei variants derived from Queensland clinical isolates

The paper profiles Burkholderia pseudomallei variants from clinical isolates to understand colony morphotype variation (CMV) using proteomics and genomics, finding that CMV is driven by regulatory mechanisms rather than genomic mutations.

Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland

The paper identifies two genetically distinct Burkholderia pseudomallei strains co-isolated from a single patient and presents their multi-omics characterization.

Whole genome sequencing reveals the emergence of a Pseudomonas aeruginosa shared strain sub-lineage among patients treated within a single cystic fibrosis centre

The paper uses whole genome sequencing to show that M3L7, a multidrug-resistant sub-type of AUST-02, emerged as a shared strain among CF patients in a single centre, with evidence of both continuous infection and cross-infection.