Evasion of neutrophil-mediated bacterial clearance in Pseudomonas aeruginosa isolates from new-onset infections in cystic fibrosis children
Kelly Kwong, Sophia Goldman, Annie Beauchamp…·Dao M. Nguyen
This study shows that Pseudomonas aeruginosa isolates from CF patients who failed eradication therapy resist neutrophil-mediated clearance due to loss of Type IV pilus-mediated twitching motility, contributing to infection persistence.