Aidan J. O’Donnell

This study models malaria parasite development and sequestration in vivo using time series data from Plasmodium chabaudi, showing parasites adjust their development to host rhythms at a cost to multiplication rates.

This study shows malaria parasites time their liver-to-blood stage transition to align with host feeding rhythms, enhancing survival and transmission.

The paper shows that malaria parasites' intraerythrocytic cycle duration is influenced by coordination with host circadian rhythms, with gene expression and pathways affected when this coordination is disrupted.