Arnab Pain

This study shows AP2-L is essential for Plasmodium liver-stage development by regulating PVM formation and host-cell interactions.

This paper develops a biohybrid sensor array inspired by insect olfaction to detect airborne pheromones and monitor early infestation of red palm weevils.

The paper identifies two genetically distinct clusters of Plasmodium malariae in Africa and finds evidence of adaptive evolution in these populations.

This study identifies PfAP2-HCR as a critical transcription factor regulating host cell remodeling in Plasmodium falciparum, essential for parasite survival and transmission.

This study examines changes in the H3K27me3 epigenetic mark in Theileria annulata-transformed macrophages during attenuation, finding increased global H3K27me3 levels and broader genomic distribution without major transcriptional changes.

plasmoRUtils streamlines bioinformatics analysis for Apicomplexan parasites by integrating data retrieval, harmonization, and analysis tools within R.

This study identifies NEK1's role in organizing the MTOC and ensuring kinetochore attachment during rapid mitosis in Plasmodium male gamete formation.

The paper examines how Plasmodium falciparum parasites from cerebral malaria and uncomplicated malaria affect human brain endothelial cells, finding no significant correlation between clinical syndrome type and endothelial gene expression responses.

This study identifies PfAP2-MRP as a master regulator controlling parasite growth, chromatin structure, and var gene expression during malaria parasite blood stages.

The paper sequences four Perkinsus mitochondrial genomes, identifies conserved frameshifts in all genes, and proposes a decoding mechanism involving unused codons.

The paper analyzes the pangenome of Rhizoctonia solani isolates and develops a database, RsolaniDB, to facilitate research on its genetic diversity and pathogenicity.

The paper sequences the genome of Plasmodium simium to study its evolutionary history and identify genetic adaptations enabling host-switching to humans.

This paper develops genetic tools for Perkinsus marinus, enabling efficient transgene expression and selection, and identifies genomic integration mechanisms.

The paper generates high-quality genomes and phenotypes for ten Plasmodium vinckei isolates, revealing genomic diversity, selection pressures, and potential for genetic manipulation.

This study identifies and characterizes the first pheromone receptor in the red palm weevil, showing its role in detecting pheromone compounds and correlating with mating success.

assayM monitors mutations in SARS-CoV-2 diagnostic assays by analyzing global genome datasets against WHO and custom primer sequences.

The paper defines a genetic barcoding scheme using 10-nucleotide classifiers to classify SARS-CoV-2 clades from genomic data, achieving high accuracy in identifying circulating viral populations.

The paper identifies the envelope protein E as a therapeutic target for COVID-19 and suggests existing drugs that inhibit this protein could prevent ARDS.

The paper shows that malaria parasites' intraerythrocytic cycle duration is influenced by coordination with host circadian rhythms, with gene expression and pathways affected when this coordination is disrupted.

The paper identifies GZMA and RASGRP1 as tumor suppressors in Theileria-transformed bovine macrophages and human B-lymphoma cells through transcriptomic and functional analyses.

This paper introduces a method to identify genetic drivers of multiple phenotypes in malaria parasites by combining LGS, sequencing, and mathematical modeling, demonstrating its effectiveness in detecting novel alleles for growth rate and strain-specific immunity.