Author

Britta Lötstedt

Broad InstituteORCID 0000-0003-3545-5489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:spatial transcriptomics· 4 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Aviv RegeviD· 4 shared Sanja VickovićiD· 4 shared Aase Haj HensvoldiD· 1 shared Aidan C. DalyiD· 1 shared Anca I. CatrinaiD· 1 shared Åsa SegerstolpeiD· 1 shared Daniel DomoviciD· 1 shared Denis SchapiroiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersGenomics

Aviv RegevORCID

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4 papers

Recent·Most cited

Tissue and cellular spatiotemporal dynamics in colon aging

Aidan C. Daly, Francesco Cambuli, Tarmo Äijö, Britta Lötstedt, Nemanja Despot Marjanovic, Sara Fernandez, Olena Kuksenko, Matthew Smith-Erb, Daniel Domovic, Nicholas Van Wittenberghe, Eugene Drokhlyansky, Gabriel Kenneth Griffin, Hemali P. Phatnani, Richard Bonneau, Aviv Regev, Sanja Vicković

This study creates a spatial and cellular atlas of the colon across age groups using spatial transcriptomics and single nucleus RNA-seq, identifying age-related molecular gradients and multicellular programs.

Nature Biotechnology · Oct 22, 2025Peer-reviewedSystems Biology

Spatial host-microbiome sequencing

Britta Lötstedt, Martin Stražar, Ramnik J. Xavier, Aviv Regev, Sanja Vicković

This paper introduces a spatial sequencing method to study host-microbiome interactions in the mouse gut using deep learning for spatial niche detection.

Nature Biotechnology · Nov 20, 2023Peer-reviewedGenomics

Three-dimensional spatial transcriptomics uncovers cell type dynamics in the rheumatoid arthritis synovium

Sanja Vicković, Denis Schapiro, Konstantin Carlberg, Britta Lötstedt, Ludvig Larsson, Franziska Hildebrandt, Marina Korotkova, Aase Haj Hensvold, Anca I. Catrina, Peter Karl Sorger, Vivianne Malmström, Aviv Regev, Patrik L. Ståhl

This study uses spatial transcriptomics to analyze cell type dynamics in rheumatoid arthritis synovium, revealing chemokine-driven interactions in inflamed tissue.

Communications Biology · Feb 11, 2022Peer-reviewedGenomics

SM-Omics: An automated platform for high-throughput spatial multi-omics

Sanja Vicković, Britta Lötstedt, Johanna Klughammer, Simon Mages, Åsa Segerstolpe, Orit Rozenblatt–Rosen, Aviv Regev

SM-Omics is a platform that combines spatial transcriptomics and proteomics to analyze tissue samples at scale.

Nature Communications · Feb 10, 2022Peer-reviewedGenomics