Author

木村聡

Brigham and Women's HospitalORCID 0000-0003-3555-5877Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Herbert Guimarães de Sousa SilvaiD· 2 shared Júlia Pinheiro Chagas da CunhaiD· 2 shared Matthew K. WaldoriD· 2 shared Ana Paula de Jesus MenezesiD· 1 shared Ariel Mariano SilberiD· 1 shared David S. Pires· 1 shared Janaina F. Nascimento· 1 shared Marilene Souza Braga· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersMolecular Biology

Herbert Guimarães de Sousa SilvaORCID

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2 papers

Recent·Most cited

Remodeling of tRNA modification in Trypanosoma cruzi life forms

Herbert Guimarães de Sousa Silva, Janaina F. Nascimento, Marilene Souza Braga, Ana Paula de Jesus Menezes, Ariel Mariano Silber, Matthew K. Waldor, Júlia Pinheiro Chagas da Cunha, 木村聡

This study profiles tRNA modifications in different life stages of Trypanosoma cruzi and finds that hydroxywybutosine modification levels regulate metacyclogenesis.

PLoS Pathogens · May 26, 2026Peer-reviewedMolecular Biology

Integrating tDNA Epigenomics and Expression with Codon Usage Unravel an Intricate Connection with Protein Expression Dynamics in Trypanosoma cruzi

Herbert Guimarães de Sousa Silva, 木村聡, P. L. C. P. de Lima, David S. Pires, Matthew K. Waldor, Júlia Pinheiro Chagas da Cunha

The paper investigates codon usage bias and its relationship with protein expression in Trypanosoma cruzi by integrating tRNA sequencing and transcriptomic data.

mBio · Aug 11, 2025Peer-reviewedCell Biology