Fabrizio Piras

This paper introduces a Hodge-Laplacian framework to analyze higher-order topology in OCD brain networks, identifying loop-level abnormalities not detectable by conventional functional connectivity analysis.

CALM-VLM improves confidence and reliability in brain MRI classification by calibrating vision-language models and enabling selective prediction.

This study identifies small but consistent anatomical correlates of negative symptom dimensions in schizophrenia, linking them to prefrontal cortical thickness and limbic subcortical volumes.

This paper develops a deep autoencoder for detecting brain morphology anomalies in bipolar disorder using the StratiBip dataset, finding greater and more heterogeneous deviations in BD patients.

The paper analyzes exome data from 22,319 individuals to identify rare CNVs and 22q11.21 dosage as risk factors for Alzheimer's disease.

The paper evaluates factors affecting brain-age prediction models using structural neuroimaging data from 35,683 individuals, finding optimal model performance with no site harmonization, age-binning, and a sample size of over 1,600.

This study examines structural brain heterogeneity in schizophrenia using multimodal MRI data from the ENIGMA dataset, finding higher frontotemporal heterogeneity and left parahippocampal homogeneity in patients.

The paper identifies high-priority missense variants in SORL1 associated with increased Alzheimer's Disease risk and earlier onset, suggesting clinical counseling considerations for carriers.

This study compares data-driven and theory-based biomarkers for predicting chronic motor outcomes after stroke, finding data-driven models perform better, especially when using structural disconnection measures.

The paper benchmarks and optimizes a normative modeling framework for brain morphometry across the lifespan using MFPR, showing excellent accuracy and stability.

This study finds that smaller ipsilesional hippocampal volume is associated with worse upper limb sensorimotor impairment in chronic stroke patients, with a stronger effect in women.

This study shows that global brain health, measured by brain age, influences post-stroke sensorimotor outcomes and mediates the effect of lesion damage.

This study finds that smaller spared subcortical nuclei are linked to worse sensorimotor outcomes after stroke, varying by time since stroke and type of impairment.

This study identifies white matter microstructural alterations in adult OCD patients and links them to clinical features, while finding no such abnormalities in pediatric patients.

The paper develops deep learning models to assess the quality of subcortical brain shape models from MRI, reducing human rater time by 46-70%.

This work uses machine learning to automate quality control of 3D brain shape models, reducing human workload by 30-70% across multiple datasets and diseases.