Ibtissam Jabre

This paper shows that L-lactate promotes gametocytogenesis in Plasmodium falciparum by inducing histone lactylation and regulating the GDV-1/AP2-G epigenetic pathway.

This study identifies lactylated histones as markers of virulence genes in Plasmodium falciparum, showing their enrichment at genes involved in host-cell remodelling and dynamic regulation across the cell cycle.

The paper identifies histone lactylation as a new epigenetic mark in malaria parasites, showing its metabolic sensitivity and differential abundance between species.