Author

Marcelo Mendonça

Champalimaud FoundationORCID 0000-0003-3587-8553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Rui M. CostaiD· 2 shared Andreas KlausiD· 1 shared Cristina AlcaceriD· 1 shared Iván CastelaiD· 1 shared Joaquim Alves da SilvaiD· 1 shared Jose Angel ObesoiD· 1 shared Ledia F. HernándeziD· 1 shared Maria Angela CenciiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Rui M. CostaORCID

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2 papers

Recent·Most cited

Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering

Cristina Alcacer, Andreas Klaus, Marcelo Mendonça, Sara F. Abalde, Maria Angela Cenci, Rui M. Costa

The paper identifies two main dyskinesia types and pathological rotations in a mouse model of LID using high-resolution motion sensors and video recordings, linking them to abnormal activity in specific striatal SPN ensembles.

Cell Reports · Jul 1, 2025Peer-reviewedNeuroscience

Transient dopamine neuron activity precedes and encodes the vigor of contralateral movements

Marcelo Mendonça, Joaquim Alves da Silva, Ledia F. Hernández, Iván Castela, Jose Angel Obeso, Rui M. Costa

This study shows that dopamine neurons in the substantia nigra pars compacta encode contralateral movement vigor through transient activity, not general motivation.

Current Biology · Feb 19, 2024Peer-reviewedNeuroscience