Author

Aaron J. Middlebrook

BD Biosciences (United States)ORCID 0000-0003-3597-5636Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Aaron J. TyznikiD· 1 shared Bjoern PetersiD· 1 shared Cheryl KimiD· 1 shared Denise Hinz· 1 shared Julie G. BureliD· 1 shared Louise M. D’CruziD· 1 shared Thomas J. ScribaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Aaron J. TyznikORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintSep 8, 2026

✦ In-depth digest

A high-resolution blood immune cell doublet atlas via imaging spectral cytometry

Cheryl Kim, Denise Hinz, Aaron J. Middlebrook…·Julie G. Burel

Image-based gating on an imaging spectral cytometer resolves 12 high-purity immune doublet types in human blood; in tuberculosis, doublet frequencies are unchanged but tightly contacting T cell-monocyte doublets increase.

1 citation

humanimaging

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