Author

Zicheng Wang

Chinese University of Hong Kong, ShenzhenORCID 0000-0003-3608-6830Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zicheng Wang1 paper · Columbia University Irving Medical Center

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:human· 1 Research Focus:trajectory inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jason M. SheltzeriD· 1 shared Lauren Mills· 1 shared Nicole MaeseriD· 1 shared Ruping SuniD· 1 shared Scott M. DehmiD· 1 shared Xuanming ZhangiD· 1 shared Yichen ChuiD· 1 shared Yunong XiaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Jason M. SheltzerORCID

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2 papers

Recent·Most cited

Mutation Order and Selection Shape Intratumor Heterogeneity in Tumor Evolution

Yichen Chu, 盛小夏 Sheng Xiaoxia, Xuanming Zhang, Zicheng Wang

This study develops a branching-process model to show how mutation order and selection shape intratumor heterogeneity by analyzing pathway-specific clone dynamics and fitness effects.

bioRxiv · Sep 28, 2026 · PreprintCancer Biology

Evolving copy number gains promote tumor expansion and bolster mutational diversification

Zicheng Wang, Yunong Xia, Lauren Mills, Αθανάσιος Ν. Νικολακόπουλος, Nicole Maeser, Scott M. Dehm, Jason M. Sheltzer, Ruping Sun

The paper estimates the arrival time of clonal copy number gains in tumors and shows they promote mutational diversification and malignant growth.

Nature Communications · Mar 6, 2024Peer-reviewedGenomics