Xuanming Zhang

This study develops a branching-process model to show how mutation order and selection shape intratumor heterogeneity by analyzing pathway-specific clone dynamics and fitness effects.

This study models CISH-KO TIL therapy in gastrointestinal cancer, finding that T-cell persistence and endogenous competition are key determinants of treatment response.

This study investigates the pro-angiogenic effects of GA preparations in zebrafish, finding that diammonium glycyrrhizinate injection (DGI) activates the mTOR/HIF-1 signaling pathway to promote angiogenesis.

The paper develops nanoTIPseq to profile L1 retrotransposons in mouse genomes, identifying both annotated and unannotated insertions with high sensitivity.