Author

Asma Naseem

University College LondonORCID 0000-0003-3612-2336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adrian James ThrasheriD· 2 shared Alessia CavazzaiD· 2 shared Federica ZinghirinoiD· 2 shared Giandomenico TurchianoiD· 2 shared Antonio CarusilloiD· 1 shared Carlo CiprianiiD· 1 shared Daniela CesanaiD· 1 shared Eduardo Gómez‐CastañedaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Adrian James ThrasherORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular Therapy AdvancesPeer-reviewedJul 22, 2026

In-Depth Characterization of Stem Cell Potency and Genotoxicity for Clinical-Scale Ex Vivo CRISPR/Cas9 Gene Editing

Asma Naseem, Winston Vetharoy, Thomas E. Whittaker…·Alessia Cavazza

This study develops a clinical-compliant framework for ex vivo CRISPR/Cas9 gene editing of HSPCs to correct WAS, showing improved engraftment and a favorable safety profile with minimal off-target effects.

1 citation

humanCRISPR screen

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Molecular BiologyHuman Gene TherapyPeer-reviewedJan 22, 2024

CRISPR/Cas9-based disease modelling and functional correction of Interleukin 7 Receptor alpha Severe Combined Immunodeficiency in T-lymphocytes and hematopoietic stem cells

Rajeev Rai, Zohar Steinberg, Marianna Romito…·Alessia Cavazza

The paper develops a CRISPR/Cas9-based gene editing strategy to correct IL7R-SCID in T cells and HSPCs, restoring IL7R expression and T cell development.

15 citations

humanexperimental assay

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