Elizabeth I. Flandreau

This paper performs two meta-analyses of transcriptional data from rodent brain regions to identify shared gene expression changes across antidepressant categories.

This paper performs a meta-analysis of antipsychotic effects on frontal cortex transcriptomes in rodents and non-human primates, identifying 63 differentially expressed genes.

This paper identifies 133 consistently differentially expressed genes in the prefrontal cortex of chronically stressed mice across multiple stress paradigms and finds convergence with human psychiatric disorder gene expression patterns.

This study performs a meta-analysis of rodent sleep deprivation transcriptome data to identify consistently differentially expressed genes across multiple studies.

This paper performs a meta-analysis of three mouse datasets to identify stress-related gene expression changes in whole blood and links them to immune dysregulation and cellular aging.

This paper performs a meta-analysis of gene expression data from five datasets to identify long-term effects of early life stress on the prefrontal cortex, finding consistent downregulation of myelin-related genes and upregulation of genes related to Major Depressive Disorder.

The paper introduces Brain.GMT, a curated database of brain-related gene sets to improve interpretation of neuroscience studies by addressing the limitations of traditional gene ontology databases.