Brittany Rupp

This paper presents a single-cell and spatial proteotranscriptomic atlas of human oral tissues, identifying fibroblasts as key immunoregulatory hubs and revealing changes in disease states.

This study reveals how persistent intracellular bacterial macromolecules in mucosal epithelial cells drive inflammatory signaling, offering new insights into microbial-host interactions and their potential impact on inflammatory disease treatment and drug efficacy.

This study analyzes immune cell dynamics in HPV-negative HNSCC using single-cell RNA sequencing to identify molecular signatures and communication patterns associated with disease progression.