Rômulo Gonçalves Agostinho Galvani

LysoDCs in Peyer's patches program compartmentalized microbiota-specific Th17 responses

The paper shows that Peyer's patch LysoDCs generate microbiota-specific Th17 responses distinct from those in mesenteric lymph nodes, with functional consequences for mucosal immunity.

AID facilitates TET2 demethylation of Irf4 for plasma cell fate in germinal center B cells

This study shows AID deficiency in B cells leads to reduced IRF4 expression and impaired plasma cell differentiation due to disrupted TET2-mediated demethylation of the Irf4 promoter.

The Single-Cell Landscape of Peripheral and Tumor-infiltrating Immune Cells in HPV- HNSCC

This study analyzes immune cell dynamics in HPV-negative HNSCC using single-cell RNA sequencing to identify molecular signatures and communication patterns associated with disease progression.