Molecular BiologyACS Chemical BiologyPeer-reviewed
The importance of charge in perturbing the aromatic glue stabilizing the protein-protein interface of homodimeric tRNA-guanine transglycosylase
Andreas Nguyen, Dzung Nguyen, Tran Xuan Phong Nguyen…·Klaus Reuter
The paper investigates how charge affects the stability of the homodimeric tRNA-guanine transglycosylase (Tgt) interface, showing that protonation of a histidine destabilizes the dimer at acidic pH.