Author

Dzung Nguyen

Agency for Science, Technology and Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Organism:Xenopus· 1

Frequent Co-Authors

A. HeineiD· 1 shared Andreas Nguyen· 1 shared Anne-Sophie Tournillon· 1 shared Aspen Rene GutgselliD· 1 shared Daniel Grosser· 1 shared Francesco V. ReddavideiD· 1 shared François DebaeneiD· 1 shared Gerhard KlebeiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

A. HeineORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Discovery of Membrane Channel Modulators via DNA-Encoded Library Screening Using Native-Like Membrane Protein Nanoparticles

Francesco V. Reddavide, Trine Lisberg Toft‐Bertelsen, Ieva Drulyte, Aspen Rene Gutgsell, Dzung Nguyen, Sara Bonetti, Katerina Vafia, Anne-Sophie Tournillon, Stephan Heiden, Daniel Grosser, Katarina Iric, Veronica Diez, Nanna MacAulay, Stefan Geschwindner, Michael Thompson, , Robin Löving

This paper develops a method to discover PANX1 modulators using DNA-encoded library screening with stabilized membrane protein nanoparticles and validates hits through biophysical and electrophysiological assays.

Scientific Reports · Jun 15, 2026Peer-reviewedBiochemistry

The importance of charge in perturbing the aromatic glue stabilizing the protein-protein interface of homodimeric tRNA-guanine transglycosylase

Andreas Nguyen, Dzung Nguyen, Tran Xuan Phong Nguyen, Maurice Sebastiani, Stefanie Dörr, Oscar Hernandez‐Alba, François Debaene, Sarah Cianférani, A. Heine, Gerhard Klebe, Klaus Reuter

The paper investigates how charge affects the stability of the homodimeric tRNA-guanine transglycosylase (Tgt) interface, showing that protonation of a histidine destabilizes the dimer at acidic pH.

ACS Chemical Biology · Nov 9, 2020Peer-reviewedMolecular Biology