Author

Laura E. van Rooijen

Utrecht UniversityORCID 0000-0003-3693-158XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

‎Berend SneliD· 3 shared Eelco C. TromeriD· 2 shared Geert J.P.L. KopsiD· 2 shared Mikko J. FrilanderiD· 2 shared Ali OghabianiD· 1 shared Antto J. NorppaiD· 1 shared Bas de WolfiD· 1 shared Bertrand IsidoriD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

‎Berend SnelORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 28, 2025

Unconventional components complement the cryptic kinetochore of the ciliate Tetrahymena thermophila

Emine I. Ali, Maximilian W.D. Raas, Laura E. van Rooijen…·Geert J.P.L. Kops

This study identifies 16 kinetochore proteins in Tetrahymena thermophila, revealing both conventional and unconventional components that contribute to its unique kinetochore structure.

DOI 10.1101/2025.11.28.691167

proteomicsexperimental assay

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedMar 11, 2024

Distinct functions for the paralogous RBM41 and U11/U12-65K proteins in the minor spliceosome

Antto J. Norppa, Iftekhar Mahmud Chowdhury, Laura E. van Rooijen…·Mikko J. Frilander

This study identifies RBM41 as a paralog of U11/U12-65K in the minor spliceosome, showing distinct roles in splicing and spliceosome dynamics.

11 citations

humanexperimental assay

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Molecular BiologybioRxivPreprintAug 6, 2020

Chromosomal instability by mutations in a novel specificity factor of the minor spliceosome

Bas de Wolf, Ali Oghabian, Maureen V. Akinyi…·Geert J.P.L. Kops

The paper identifies biallelic mutations in CENATAC as a cause of constitutional aneuploidy by disrupting minor intron splicing and causing chromosome segregation errors.

1 citation

humanwhole-exome sequencing

𝕏 PostBluesky