Eelco C. Tromer

This study identifies SFA1's role in coordinating cytoskeletal organisation, apical polarity, and cell replication during Plasmodium sexual development, showing its necessity for parasite transmission.

This study identifies Plasmodium NEK4 as a key regulator that couples meiotic initiation with zygote morphogenesis in malaria parasites.

The paper identifies GAPM2 as an IMC component in Plasmodium species and reveals its heterotrimeric complex structure and functional role in the glideosome.

This study identifies ARK1 as a critical regulator of mitosis in Plasmodium, forming a non-canonical chromosomal passenger complex with divergent INCENPs, and highlights its potential as an antimalarial target.

This study identifies molecular differences in meiosis between eupyrene and apyrene sperm production in silkworms, showing that Sxl facilitates error-prone meiosis for apyrene sperm.

This study identifies 16 kinetochore proteins in Tetrahymena thermophila, revealing both conventional and unconventional components that contribute to its unique kinetochore structure.

This study reconstructs the evolution of SMC complexes across eukaryotes, showing LECA had all four types and condensin II was repeatedly lost.

This study identifies the SUN1-ALLAN complex as critical for coordinating nuclear envelope remodeling and bipartite MTOC segregation during rapid mitosis in Plasmodium male gametogenesis.

This study investigates the kinetochore system in diplonemids, a group of protists, and suggests they may have evolved a previously unknown type of kinetochore.

This study identifies NEK1's role in organizing the MTOC and ensuring kinetochore attachment during rapid mitosis in Plasmodium male gamete formation.

This study identifies KKT14-KKT15 in kinetoplastids as divergent orthologs of Bub1/BubR1-Bub3, suggesting a unique mechanism for chromosome segregation fidelity in trypanosomes.

The paper identifies biallelic mutations in CENATAC as a cause of constitutional aneuploidy by disrupting minor intron splicing and causing chromosome segregation errors.

The paper identifies a conserved motif cassette in BubR1 essential for the spindle checkpoint through phylogenomics and functional analysis.