Derek K. O’Flaherty

This paper introduces a universal volatile buffer system using fluorinated ethylamines for native LC-MS analysis of antibody-based therapeutics, enabling broad pH range buffering and compatibility with mass spectrometry.

This study investigates how lipid acyl-chain chemistry affects membrane properties and interactions with DNA nanoprobes and coacervates, identifying a packing-dependent guiding principle for membrane interactions.

This study demonstrates that functional RNA ligase ribozymes can be assembled from short oligonucleotides using modified ligation chemistry.